Identification of Time-Invariant Biomarkers for Non-Genotoxic Hepatocarcinogen Assessment

Non-genotoxic hepatocarcinogens (NGHCs) can only be confirmed by 2-year rodent studies. Toxicogenomics (TGx) approaches using gene expression profiles from short-term animal studies could enable early assessment of NGHCs. However, high variance in the modulation of the genes had been noted among exp...

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Bibliographic Details
Main Authors: Shan-Han Huang, Ying-Chi Lin, Chun-Wei Tung
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Online Access:https://www.mdpi.com/1660-4601/17/12/4298