A review of the mechanism of action and clinical applications of sorafenib in advanced osteosarcoma

Objective: To summarise the contemporary literature regarding sorafenib and its effectiveness as a novel treatment in advanced osteosarcoma. Background: Modern treatment has seen the cure rate of osteosarcoma increase to 65%. However, in patients who do not achieve remission, prognosis is poor, as t...

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Bibliographic Details
Main Author: James Coventon
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Bone Oncology
Subjects:
ERK
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137417300520