Development, evaluation and application of 3D QSAR Pharmacophore model in the discovery of potential human renin inhibitors
<p>Abstract</p> <p>Background</p> <p>Renin has become an attractive target in controlling hypertension because of the high specificity towards its only substrate, angiotensinogen. The conversion of angiotensinogen to angiotensin I is the first and rate-limiting step of...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-12-01
|
| Series: | BMC Bioinformatics |