Rational design of a structure-switching DNA aptamer for potassium ions

Structure-switching molecules provide a unique means for analyte detection, generating a response to analyte concentration through a binding-specific conformational change between non-binding and binding-competent states. While most ligand-binding molecules are not structure switching by default, ma...

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Bibliographic Details
Main Authors: Andrew T. Catherine, Stephanie N. Shishido, Gregg A. Robbins-Welty, Amy Diegelman-Parente
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:FEBS Open Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211546314000825