Rational design of a structure-switching DNA aptamer for potassium ions
Structure-switching molecules provide a unique means for analyte detection, generating a response to analyte concentration through a binding-specific conformational change between non-binding and binding-competent states. While most ligand-binding molecules are not structure switching by default, ma...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211546314000825 |