Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase.
Beyond intracellular killing, a novel neutrophil-based antimicrobial mechanism has been recently discovered: entrapment and killing by neutrophil extracellular traps (NETs). NETs consist of extruded nuclear DNA webs decorated with granule proteins. Although NET formation is an important innate immun...
Main Authors: | Balázs Rada, Meghan A Jendrysik, Lan Pang, Craig P Hayes, Dae-Goon Yoo, Jonathan J Park, Samuel M Moskowitz, Harry L Malech, Thomas L Leto |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3544820?pdf=render |
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