Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase.

Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase.

Beyond intracellular killing, a novel neutrophil-based antimicrobial mechanism has been recently discovered: entrapment and killing by neutrophil extracellular traps (NETs). NETs consist of extruded nuclear DNA webs decorated with granule proteins. Although NET formation is an important innate immun...

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Bibliographic Details
Main Authors: Balázs Rada, Meghan A Jendrysik, Lan Pang, Craig P Hayes, Dae-Goon Yoo, Jonathan J Park, Samuel M Moskowitz, Harry L Malech, Thomas L Leto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544820?pdf=render

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http://europepmc.org/articles/PMC3544820?pdf=render

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