A Newfound association between MDC1 functional polymorphism and lung cancer risk in Chinese.

Mediator of DNA damage checkpoint protein 1 (MDC1) plays an early and core role in Double-Strand Break Repair (DDR) and ataxia telangiectasia-mutated (ATM) mediated response to DNA double-strand breaks (DSBs), and thus involves the pathogenesis of several DNA damage-related diseases such as cancer....

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Bibliographic Details
Main Authors: Bo Wang, Lisha Zhang, Fuman Qiu, Wenxiang Fang, Jieqiong Deng, Yifeng Zhou, Jiachun Lu, Lei Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4157800?pdf=render