Location matters: highly divergent protein levels in samples from different CNS compartments in a clinical trial of rituximab for progressive MS

Location matters: highly divergent protein levels in samples from different CNS compartments in a clinical trial of rituximab for progressive MS

Abstract Background The relationship between proteins in different CNS extracellular compartments is unknown. In this study the levels of selected proteins in three compartments in people with progressive multiple sclerosis (PMS) were compared. Methods During an open label, phase 1b study on intrave...

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Bibliographic Details
Main Authors: Joakim Bergman, Anders Svenningsson, Per Liv, Tommy Bergenheim, Joachim Burman
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Fluids and Barriers of the CNS
Subjects:
Cerebrospinal fluid
Microdialysis
Ventricular CSF
Lumbar CSF
Interstitial fluid
CSF compartments
Online Access:http://link.springer.com/article/10.1186/s12987-020-00205-4

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http://link.springer.com/article/10.1186/s12987-020-00205-4

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