Canine platelets express functional Toll-like receptor-4: lipopolysaccharide-triggered platelet activation is dependent on adenosine diphosphate and thromboxane A2 in dogs

Canine platelets express functional Toll-like receptor-4: lipopolysaccharide-triggered platelet activation is dependent on adenosine diphosphate and thromboxane A2 in dogs

Abstract Background Functional Toll-like receptor 4 (TLR4) has been characterized in human and murine platelets indicating that platelets play a role in inflammation and hemostasis during sepsis. It is unclear whether canine platelets could express functional TLR4 by responding to its ligand, lipopo...

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Bibliographic Details
Main Authors: Ronald H. L. Li, Nghi Nguyen, Fern Tablin
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Veterinary Research
Subjects:
Sepsis
Thrombosis
Platelet-priming
Inflammation
Aspirin
Pattern recognition receptor
Online Access:http://link.springer.com/article/10.1186/s12917-019-1997-3

Internet

http://link.springer.com/article/10.1186/s12917-019-1997-3

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