LGI1 governs neuritin-mediated resilience to chronic stress

Depression is accompanied by neuronal atrophy and decreased neuroplasticity. Leucine-rich glioma-inactivated protein 1 (LGI1), a metastasis suppressor, plays an important role in the development of CNS synapses. We found that LGI1 expression was reduced in the hippocampi of mice that underwent chron...

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Main Authors: Seung Hoon Lee, Nam-Shik Kim, Miyeon Choi, Seung Yeon Ko, Sung Eun Wang, Hye-Ryeong Jo, Jee Young Seo, Yong-Seok Kim, Hyun Jin Kim, Hyun-Yong Lee, Joung-Hun Kim, Hyeon Son
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521000813