An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets

Abstract Background Host immune response is coordinated by a variety of different specialized cell types that vary in time and location. While host immune response can be studied using conventional low-dimensional approaches, advances in transcriptomics analysis may provide a less biased view. Yet,...

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Bibliographic Details
Main Authors: Arezo Torang, Paraag Gupta, David J. Klinke
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-2994-z