Mesenchymal stromal cell-derived exosomes improve pulmonary hypertension through inhibition of pulmonary vascular remodeling

Mesenchymal stromal cell-derived exosomes improve pulmonary hypertension through inhibition of pulmonary vascular remodeling

Abstract Background Pulmonary hypertension (PH) is a life-threatening disease characterized by pulmonary vascular remodeling, right ventricular hypertrophy and failure. So far no effective treatment exists for this disease; hence, novel approaches are urgently needed. The aim of the present research...

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Bibliographic Details
Main Authors: Shanshan Zhang, Xiaoli Liu, Li Li Ge, Kailin Li, Yongchao Sun, Fang Wang, Ying Han, Chao Sun, Jue Wang, Wen Jiang, Qian Xin, Chaoyue Xu, Yuan Chen, Ou chen, Zhaohua Zhang, Yun Luan
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Respiratory Research
Subjects:
Pulmonary hypertension
Exosomes
Pulmonary vascular remodeling
Wnt5a
Online Access:http://link.springer.com/article/10.1186/s12931-020-1331-4

Internet

http://link.springer.com/article/10.1186/s12931-020-1331-4

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