Applications of CRISPR-Cas9 Technology to Genome Editing in Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is an aggressive malignancy of the brain and spinal cord with a poor life expectancy. The low survivability of GBM patients can be attributed, in part, to its heterogeneity and the presence of multiple genetic alterations causing rapid tumor growth and resistance to con...

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Bibliographic Details
Main Authors: Nadia Al-Sammarraie, Swapan K. Ray
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/9/2342