Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice.

BACKGROUND:We have reported that WNT10A plays a critical role in the growth of fibroblasts/myofibroblasts and microvascular endothelial cells, i.e.; wound healing/scarring. To ascertain the in vivo regulatory, central functions of WNT10A, we examined the net effects of WNT10A depletion using WNT10A-...

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Bibliographic Details
Main Authors: Ke-Yong Wang, Sohsuke Yamada, Hiroto Izumi, Manabu Tsukamoto, Tamiji Nakashima, Takashi Tasaki, Xin Guo, Hidetaka Uramoto, Yasuyuki Sasaguri, Kimitoshi Kohno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5875851?pdf=render