The roles of urine interleukin-13, CD80, CD28, matrix metalloproteinase-2 and granzyme B in the pathogenesis of childhood minimal change nephrotic syndrome

The roles of urine interleukin-13, CD80, CD28, matrix metalloproteinase-2 and granzyme B in the pathogenesis of childhood minimal change nephrotic syndrome

Objective: Minimal change disease (MCD) is the most common cause of nephrotic syndrome in childhood but its pathogenesis remains poorly understood. A T-cell-derived factor or factors were initially alleged as contributing to the disease pathogenesis. However, podocyte CD80 expression is now a commo...

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Bibliographic Details
Main Authors: Cengiz Zeybek, Duygu Övünç Hacıhamdioğlu, Süleyman Tolga Yavuz, Aysel Pekel, Cihangir Akgün, Burcu Bulum, Kaan Gülleroğlu, Aslı Kantar, Aslı Kavaz, Uğur Muşabak, Fatoş Yalçınkaya, Esra Baskın, Faysal Gök
Format: Article
Language:English
Published: Modestum Publishing LTD 2014-09-01
Series:Journal of Clinical and Experimental Investigations
Subjects:
Minimal change disease
Interleukin-13
B7 proteins
MMP-2
Online Access:http://www.jceionline.org/upload/sayi/24/JCEI-00999.pdf

Internet

http://www.jceionline.org/upload/sayi/24/JCEI-00999.pdf

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