Comparative Kinetics of Acetyl- and Butyryl-Cholinesterase Inhibition by Green Tea Catechins|Relevance to the Symptomatic Treatment of Alzheimer’s Disease

Alzheimer’s disease (AD) is characterised by the apoptosis of cholinergic neurons and the consequent attenuation of acetylcholine mediated neurotransmission, resulting in neurodegeneration. Acetyl-cholinesterase (AChE) and butyryl-cholinesterase (BuChE) are attractive therapeutic targets in the trea...

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Bibliographic Details
Main Authors: Edward J. Okello, Joshua Mather
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/12/4/1090