Bexarotene Exerts Protective Effects Through Modulation of the Cerebral Vascular Smooth Muscle Cell Phenotypic Transformation by Regulating PPARγ/FLAP/LTB After Subarachnoid Hemorrhage in Rats

Bexarotene Exerts Protective Effects Through Modulation of the Cerebral Vascular Smooth Muscle Cell Phenotypic Transformation by Regulating PPARγ/FLAP/LTB After Subarachnoid Hemorrhage in Rats

Vascular smooth muscle cells (VSMCs) play an important role after a subarachnoid hemorrhage (SAH). The changes in VSMCs following bexarotene treatment after SAH are unknown. In the present study, neurological impairment, decreased cerebral cortical blood flow and transformation of cerebral VSMCs fro...

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Bibliographic Details
Main Authors: Zhaosi Zhang, Guosheng Zhao, Liu Liu, Junchi He, Rami Darwazeh, Han Liu, Hong Chen, Chao Zhou, Zongduo Guo, Xiaochuan Sun
Format: Article
Language:English
Published: SAGE Publishing 2019-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689719842161

Internet

https://doi.org/10.1177/0963689719842161

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