The blood-brain barrier studied in vitro across species.

The blood-brain barrier (BBB) is formed by brain capillary endothelial cells (BECs) supported by pericytes and astrocytes. The BBB maintains homeostasis and protects the brain against toxic substances circulating in the blood, meaning that only a few drugs can pass the BBB. Thus, for drug screening,...

Full description

Bibliographic Details
Main Authors: Maj Schneider Thomsen, Nanna Humle, Eva Hede, Torben Moos, Annette Burkhart, Louiza Bohn Thomsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0236770