Inhaled Anesthetics Promote Albumin Dimerization through Reciprocal Exchange of Subdomains

Inhaled anesthetics affect protein-protein interaction, but the mechanisms underlying these effects are still poorly understood. We examined the impact of sevoflurane and isoflurane on the dimerization of human serum albumin (HSA), a protein with anesthetic binding sites that are well characterized....

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Bibliographic Details
Main Authors: Benjamin J. Pieters, Eugene E. Fibuch, Joshua D. Eklund, Norbert W. Seidler
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2010/516704