Proteomics and phosphoproteomics study of LCMT1 overexpression and oxidative stress: overexpression of LCMT1 arrests H2O2-induced lose of cells viability

Proteomics and phosphoproteomics study of LCMT1 overexpression and oxidative stress: overexpression of LCMT1 arrests H2O2-induced lose of cells viability

Objectives: Protein phosphatase 2A (PP2A), a major serine/threonine phosphatase, is also known to be a target of ROS. The methylation of PP2A can be catalyzed by leucine carboxyl methyltransferase-1 (LCMT1), which regulates PP2A activity and substrate specificity. Methods: In the previous study, we...

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Bibliographic Details
Main Authors: Xinhang Wang, Shen Tang, Fu Qin, Yuyang Liu, Ziwei Liang, Haiqing Cai, Laiming Mo, Deqiang Xiao, Songcao Guo, Yiqiang Ouyang, Bin Sun, Cailing Lu, Xiyi Li
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Redox Report
Subjects:
lcmt1
oxidative stress
proteomics
hemoglobin
mapk3
rho signal transduction
Online Access:http://dx.doi.org/10.1080/13510002.2019.1595332

Internet

http://dx.doi.org/10.1080/13510002.2019.1595332

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