Common biochemical properties of metabolic genes recurrently dysregulated in tumors

Common biochemical properties of metabolic genes recurrently dysregulated in tumors

Abstract Background Tumor initiation and progression are associated with numerous metabolic alterations. However, the biochemical drivers and constraints that contribute to metabolic gene dysregulation are unclear. Methods Here, we present MetOncoFit, a computational model that integrates 142 metabo...

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Bibliographic Details
Main Authors: Krishnadev Oruganty, Scott Edward Campit, Sainath Mamde, Costas A. Lyssiotis, Sriram Chandrasekaran
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cancer & Metabolism
Subjects:
Metabolic modeling
Genomics
Transcriptomics
Machine learning
Online Access:http://link.springer.com/article/10.1186/s40170-020-0211-1

Internet

http://link.springer.com/article/10.1186/s40170-020-0211-1

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