Highly efficient site-specific transgenesis in cancer cell lines

<p>Abstract</p> <p>Background</p> <p>Transgenes introduced into cancer cell lines serve as powerful tools for identification of genes involved in cancer. However, the random nature of genomic integration site of a transgene highly influences the fidelity, reliability an...

Full description

Bibliographic Details
Main Authors: Michael Iacovos P, Monetti Claudio, Chiu Anthony C, Zhang Puzheng, Baba Takeshi, Nishino Koichiro, Agha-Mohammadi Siamak, Woltjen Knut, Sung Hoon-Ki, Nagy Andras
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Molecular Cancer
Subjects:
Online Access:http://www.molecular-cancer.com/content/11/1/89