CRISPR-Associated Factor Csa3b Regulates CRISPR Adaptation and Cmr-Mediated RNA Interference in Sulfolobus islandicus

CRISPR-Associated Factor Csa3b Regulates CRISPR Adaptation and Cmr-Mediated RNA Interference in Sulfolobus islandicus

Acquisition of spacers confers the CRISPR–Cas system with the memory to defend against invading mobile genetic elements. We previously reported that the CRISPR-associated factor Csa3a triggers CRISPR adaptation in Sulfolobus islandicus. However, a feedback regulation of CRISPR adaptation remains unc...

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Bibliographic Details
Main Authors: Qing Ye, Xueqiao Zhao, Jilin Liu, Zhifeng Zeng, Zhufeng Zhang, Tao Liu, Yingjun Li, Wenyuan Han, Nan Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Microbiology
Subjects:
Sulfolobus islandicus
CRISPR adaptation
Cmr
transcriptional regulation
Csa3b
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.02038/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.02038/full

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