TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage

TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage

Abstract Background Innate immunity can facilitate early brain injury (EBI) following subarachnoid hemorrhage (SAH). Numerous studies suggest that pyroptosis could exacerbate extracellular immune responses by promoting secretion of inflammatory cytokines. Transforming growth factor-β-activated kinas...

Full description

Bibliographic Details
Main Authors: Pengfei Xu, Chunrong Tao, Yuyou Zhu, Guoping Wang, Lingqi Kong, Wenyu Li, Rui Li, Juanji Li, Chao Zhang, Li Wang, Xinfeng Liu, Wen Sun, Wei Hu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Neuroinflammation
Subjects:
Subarachnoid hemorrhage
TAK1
Pyroptosis
NLRP3 inflammasome
ROS
Online Access:https://doi.org/10.1186/s12974-021-02226-8

Internet

https://doi.org/10.1186/s12974-021-02226-8

Similar Items