Anti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6.

Thiacremonone (2, 4-dihydroxy-2, 5-dimethyl-thiophene-3-one) is an antioxidant substance as a novel sulfur compound generated from High-Temperature-High-Pressure-treated garlic. Peroxiredoxin 6 (PRDX6) is a member of peroxidases, and has glutathione peroxidase and calcium-independent phospholipase A...

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Main Authors: Miran Jo, Hyung-Mun Yun, Kyung-Ran Park, Mi Hee Park, Dong Hun Lee, Seung Hee Cho, Hwan-Soo Yoo, Yong-Moon Lee, Heon Sang Jeong, Youngsoo Kim, Jae Kyung Jung, Bang Yeon Hwang, Mi Kyeong Lee, Nam Doo Kim, Sang Bae Han, Jin Tae Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3950181?pdf=render