Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture

Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture

Neurons expressing neuropeptide orexins (hypocretins) in the lateral hypothalamus (LH) and serotonergic neurons in the dorsal raphe nucleus (DR) both play important roles in the regulation of sleep/wakefulness states, and show similar firing patterns across sleep/wakefulness states. Orexin neurons s...

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Bibliographic Details
Main Authors: Yuki C. Saito, Natsuko Tsujino, Manabu Abe, Maya Yamazaki, Kenji Sakimura, Takeshi Sakurai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neuroscience
Subjects:
sleep
wakefulness
orexin
serotonin
stress
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00892/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00892/full

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