Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1.

Epithelial to mesenchymal transition (EMT) is an essential differentiation program during tissue morphogenesis and remodeling. EMT is induced by soluble transforming growth factor β (TGF-β) family members, and restricted by vascular endothelial growth factor family members. While many downstream mol...

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Bibliographic Details
Main Authors: Russell Gould, David M Bassen, Anirikh Chakrabarti, Jeffrey D Varner, Jonathan Butcher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5189931?pdf=render