Notch1 promotes the pericyte-myofibroblast transition in idiopathic pulmonary fibrosis through the PDGFR/ROCK1 signal pathway

Notch1 promotes the pericyte-myofibroblast transition in idiopathic pulmonary fibrosis through the PDGFR/ROCK1 signal pathway

Pulmonary fibrosis: Moving signals down a notch might help A cell membrane protein called Notch1, which binds to signaling molecules outside cells and then alters the activity of genes inside the cells, might be a promising target for drugs to treat the lung damage of pulmonary fibrosis. This condit...

Full description

Bibliographic Details
Main Authors: Yi-Chun Wang, Qiong Chen, Jun-Ming Luo, Jing Nie, Qing-He Meng, Wei Shuai, Han Xie, Jia-Mei Xia, Hui Wang
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0228-0

Internet

https://doi.org/10.1038/s12276-019-0228-0

Similar Items