Candesartan prevents L-NAME-induced cardio-renal injury in spontaneously hypertensive rats beyond hypotensive effects

Our goal was to assess the cardiovascular and renal protection afforded by angiotensin II type 1-receptor blockade against NG-nitro-L-arginine methyl ester (L-NAME)-exacerbated hypertension in young spontaneously hypertensive rats (SHR), in comparison with the antihypertensive drug, hydralazine. Mal...

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Bibliographic Details
Main Authors: Daniel Casellas, Abderraouf Herizi, Annie Artuso, Albert Mimran, Bernard Jover
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2001-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/14703203010020011501