Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2

Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2

Abstract Background Inflammasomes have been found to interact with the gut microbiota, and this effect is associated with depression, but the mechanisms underlying this interaction have not been elucidated in detail. Results The locomotor activity of NLRP3 KO mice was significantly greater than that...

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Bibliographic Details
Main Authors: Yuan Zhang, Rongrong Huang, Mengjing Cheng, Lirui Wang, Jie Chao, Junxu Li, Peng Zheng, Peng Xie, Zhijun Zhang, Honghong Yao
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Microbiome
Subjects:
NLPR3
Gut microbiome
circHIPK2
Astrocyte
Depression
Online Access:http://link.springer.com/article/10.1186/s40168-019-0733-3

Internet

http://link.springer.com/article/10.1186/s40168-019-0733-3

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