CYP4F2 1347 G > A & GGCX 12970 C > G polymorphisms: frequency in north Indians & their effect on dosing of acenocoumarol oral anticoagulant

CYP4F2 1347 G > A & GGCX 12970 C > G polymorphisms: frequency in north Indians & their effect on dosing of acenocoumarol oral anticoagulant

Background & objectives: CYP4F2 and γ-glutamyl carboxylase (GGCX) have small but significant roles in the maintenance dose of coumarinic oral anticoagulants (COAs). CYP4F2 1347 G > A and GGCX 12970 C > G polymorphisms have been used in the pharmacogenetic dosing algorithms of warfarin for...

Full description

Bibliographic Details
Main Authors: Saurabh Singh Rathore, Surendra Kumar Agarwal, Shantanu Pande, Sushil Kumar Singh, Tulika Mittal, Balraj Mittal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Indian Journal of Medical Research
Subjects:
Allele frequency - anticoagulant - CYP2C9 - GGCX - north Indians - pharmacogenetics - polymorphism
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2014;volume=139;issue=4;spage=572;epage=578;aulast=Rathore

Internet

http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2014;volume=139;issue=4;spage=572;epage=578;aulast=Rathore

Similar Items