Cognitive inflexibility in obsessive-compulsive disorder and major depression is associated with distinct neural correlates.

Cognitive inflexibility in obsessive-compulsive disorder and major depression is associated with distinct neural correlates.

Obsessive-compulsive disorder (OCD) and major depressive disorder (MDD) are frequently co-morbid, and dysfunctional frontal-striatal circuits have been implicated in both disorders. Neurobiological distinctions between OCD and MDD are insufficiently clear, and comparative neuroimaging studies are ex...

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Bibliographic Details
Main Authors: Peter L Remijnse, Odile A van den Heuvel, Marjan M A Nielen, Chris Vriend, Gert-Jan Hendriks, Witte J G Hoogendijk, Harry B M Uylings, Dick J Veltman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634812?pdf=render

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http://europepmc.org/articles/PMC3634812?pdf=render

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