Identification of gene pairs through penalized regression subject to constraints

Identification of gene pairs through penalized regression subject to constraints

Abstract Background This article concerns the identification of gene pairs or combinations of gene pairs associated with biological phenotype or clinical outcome, allowing for building predictive models that are not only robust to normalization but also easily validated and measured by qPCR techniqu...

Full description

Bibliographic Details
Main Authors: Rex Shen, Lan Luo, Hui Jiang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Bioinformatics
Subjects:
Gene pair
Biomarker
Penalized regression
ADMM
Online Access:http://link.springer.com/article/10.1186/s12859-017-1872-9

Internet

http://link.springer.com/article/10.1186/s12859-017-1872-9

Similar Items