Kidney Diseases Enhance Expression of Tetraspanin-8: A Possible Protective Effect against Tubular Injury

Kidney Diseases Enhance Expression of Tetraspanin-8: A Possible Protective Effect against Tubular Injury

Background/Aims:TSPAN8 encoding tetraspanin-8 was identified as a candidate gene for immunoglobulin A nephropathy (IgAN) by a genome-wide association study using microsatellites in the Japanese population. Tetraspanin-8 is a cell surface protein that contributes to the migration and invasion of epit...

Full description

Bibliographic Details
Main Authors: Takashi Hirukawa, Qiong Wu, Kaichiro Sawada, Taiji Matsusaka, Sanae Saka, Akira Oka, Nobuhito Hirawa, Satoshi Umemura, Takatoshi Kakuta, Masayuki Endoh, Hidetoshi Inoko, Iekuni Ichikawa, Masafumi Fukagawa
Format: Article
Language:English
Published: Karger Publishers 2014-04-01
Series:Nephron Extra
Subjects:
Immunoglobulin A nephropathy
Tetraspanin
Tubulointerstitial injury
Migration
Online Access:http://www.karger.com/Article/FullText/362451

Internet

http://www.karger.com/Article/FullText/362451

Similar Items