Oxalate induces mitochondrial dysfunction and disrupts redox homeostasis in a human monocyte derived cell line

Monocytes/macrophages are thought to be recruited to the renal interstitium during calcium oxalate (CaOx) kidney stone disease for crystal clearance. Mitochondria play an important role in monocyte function during the immune response. We recently determined that monocytes in patients with CaOx kidne...

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Bibliographic Details
Main Authors: Mikita Patel, Vidhush Yarlagadda, Oreoluwa Adedoyin, Vikram Saini, Dean G. Assimos, Ross P. Holmes, Tanecia Mitchell
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717307565