Plasmodium translocon component EXP2 facilitates hepatocyte invasion

While the role of Plasmodium EXP2 protein as translocon component of blood stage parasites is established, its functional role in liver stage parasites remains unclear. Here, Mello-Vieira et al. reveal that EXP2 pore-forming activity induces hepatocyte membrane repair and hence is critical for hepat...

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Bibliographic Details
Main Authors: João Mello-Vieira, Francisco J. Enguita, Tania F. de Koning-Ward, Vanessa Zuzarte-Luís, Maria M. Mota
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19492-4