Salmonella infection upregulates the leaky protein claudin-2 in intestinal epithelial cells.

Tight junctions seal the space between adjacent epithelial cells. Mounting evidence suggests that tight junction proteins play a key role in the pathogenesis of human disease. Claudin is a member of the tight junction protein family, which has 24 members in humans. To regulate cellular function, cla...

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Bibliographic Details
Main Authors: Yong-guo Zhang, Shaoping Wu, Yinglin Xia, Jun Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3594366?pdf=render