Regulatory role of voltage-gated sodium channel β subunits in sensory neurons

Voltage-gated Na+ channels are transmembrane-bound proteins incorporating aqueous conduction pores that are highly selective for Na+. The opening of these channels results in the rapid influx of Na+ ions that depolarize the cell and drive the rapid upstroke of nerve and muscle action potentials. Whi...

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Bibliographic Details
Main Authors: Mohamed eChahine, Michael E O'Leary
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00070/full