Hypoxia-inducible factor-1α induces CX3CR1 expression and promotes the epithelial to mesenchymal transition (EMT) in ovarian cancer cells

Hypoxia-inducible factor-1α induces CX3CR1 expression and promotes the epithelial to mesenchymal transition (EMT) in ovarian cancer cells

Abstract Background Chemokines are involved in the homing of various cancer cells, including those of ovarian cancer (OvCa), to distant organs. They may also promote or inhibit cancer progression and metastasis. Hypoxia, a common phenomenon in malignant tumors, promotes cell proliferation regulated...

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Bibliographic Details
Main Authors: Santosh Kumar Singh, Manoj Kumar Mishra, Rajesh Singh
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Hypoxia
Chemokines
CX3CR1
EMT markers
Online Access:http://link.springer.com/article/10.1186/s13048-019-0517-1

Internet

http://link.springer.com/article/10.1186/s13048-019-0517-1

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