Hydroxychloroquine is associated with lower platelet activity and improved vascular health in systemic lupus erythematosus

Objective Hydroxychloroquine (HCQ) is a mainstay of therapy in the treatment of SLE. The effect of HCQ on platelets and vascular health is uncertain. We investigated the relationship between HCQ use and dose with platelet activity, platelet transcriptomics and vascular health in patients with SLE.Me...

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Main Authors: H Michael Belmont, Jill P Buyon, MacIntosh Grant Cornwell, Elliot S Luttrell-Williams, Michael Golpanian, Hanane El Bannoudi, Khrystyna Myndzar, Stuart Katz, Nathaniel R Smilowitz, Alexis Engel, Robert Clancy, Kelly Ruggles, Jeffrey S Berger
Format: Article
Language:English
Published: BMJ Publishing Group 2021-09-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/8/1/e000475.full