Identification of natural compounds targeting Annexin A2 with an anti-cancer effect

Identification of natural compounds targeting Annexin A2 with an anti-cancer effect

Abstract Annexin A2, a multifunctional tumor associated protein, promotes nuclear factor-kappa B (NF-κB) activation by interacting with NF-κB p50 subunit and facilitating its nuclear translocation. Here we demonstrated that two ginsenosides Rg5 (G-Rg5) and Rk1 (G-Rk1), with similar structure, direct...

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Bibliographic Details
Main Authors: Yu-Shi Wang, He Li, Yang Li, Hongyan Zhu, Ying-Hua Jin
Format: Article
Language:English
Published: SpringerOpen 2018-03-01
Series:Protein & Cell
Subjects:
Annexin A2
G-Rg5
G-Rk1
HCC
NF-κB
Online Access:http://link.springer.com/article/10.1007/s13238-018-0513-z

Internet

http://link.springer.com/article/10.1007/s13238-018-0513-z

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