Protein Translation and Signaling in Human Eosinophils

Protein Translation and Signaling in Human Eosinophils

We have recently reported that, unlike IL-5 and GM-CSF, IL-3 induces increased translation of a subset of mRNAs. In addition, we have demonstrated that Pin1 controls the activity of mRNA binding proteins, leading to enhanced mRNA stability, GM-CSF protein production and prolonged eosinophil (EOS) su...

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Bibliographic Details
Main Authors: Stephane Esnault, Zhong-Jian Shen, James S. Malter
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Medicine
Subjects:
eosinophils
protein translation
ribosomal S6 protein
Pin-1
IL-3
intracellular signaling
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2017.00150/full

Internet

http://journal.frontiersin.org/article/10.3389/fmed.2017.00150/full

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