Mapping Salivary Proteases in Sjögren’s Syndrome Patients Reveals Overexpression of Dipeptidyl Peptidase-4/CD26

Mapping Salivary Proteases in Sjögren’s Syndrome Patients Reveals Overexpression of Dipeptidyl Peptidase-4/CD26

Sjögren’s Syndrome (SS) is an autoimmune exocrinopathy characterized by the progressive damage of salivary and lacrimal glands associated with lymphocytic infiltration. Identifying new non-invasive biomarkers for SS diagnosis remains a challenge, and alterations in saliva composition reported in pat...

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Bibliographic Details
Main Authors: Laís Garreto, Sébastien Charneau, Samuel Coelho Mandacaru, Otávio T. Nóbrega, Flávia N. Motta, Carla N. de Araújo, Audrey C. Tonet, Flávia M. B. Modesto, Lilian M. Paula, Marcelo Valle de Sousa, Jaime M. Santana, Ana Carolina Acevedo, Izabela M. D. Bastos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
saliva
Sjögren’s syndrome
DPP4/CD26
protease inhibitors
protease activity
proteome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.686480/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.686480/full

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