Disease severity and mortality can be independently regulated in a mouse model of experimental graft versus host disease.

Graft versus host disease (GVHD) is the major limitation of allogeneic hematopoietic stem cell transplantation (HSCT) presenting high mortality and morbidity rates. However, the exact cause of death is not completely understood and does not correlate with specific clinical and histological parameter...

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Bibliographic Details
Main Authors: Rômulo G Galvani, Ramon Lemos, Rômulo B Areal, Pollyanna A Salvador, Dario S Zamboni, João Luiz M Wanderley, Adriana Bonomo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4313938?pdf=render