Role of the immunosuppressive microenvironment in immunotherapy

Immunotherapy is reshaping cancer treatment paradigms; however, response rates to immune therapies are low and depend on the host's pre-existing antitumor immunity. The tumor microenvironment is comprised of malignant cells, stroma, and extracellular molecules and can hinder immune control of t...

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Bibliographic Details
Main Authors: Garth W. Tormoen, MD, PhD, Marka R. Crittenden, MD, PhD, Michael J. Gough, PhD
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109418301507