Personalized medicine for reconstruction of critical-size bone defects – a translational approach with customizable vascularized bone tissue

Abstract Tissue engineering principles allow the generation of functional tissues for biomedical applications. Reconstruction of large-scale bone defects with tissue-engineered bone has still not entered the clinical routine. In the present study, a bone substitute in combination with mesenchymal st...

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Bibliographic Details
Main Authors: Annika Kengelbach-Weigand, Carolina Thielen, Tobias Bäuerle, Rebekka Götzl, Thomas Gerber, Carolin Körner, Justus P. Beier, Raymund E. Horch, Anja M. Boos
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00158-8