PARP Inhibitors as a Novel Treatment Strategy for Patients with BRCA-Mutated Metastatic Breast Cancer

Inhibitors of poly(ADP-ribose) polymerase (PARP), such as olaparib and talazoparib, have recently been approved as therapies for BRCA-mutated human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (BC). In addition, olaparib, as well as rucaparib and niraparib, have receiv...

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Bibliographic Details
Main Author: Katarzyna Rygiel
Format: Article
Language:English
Published: European Medical Journal 2019-11-01
Series:European Medical Journal Oncology
Subjects:
Online Access:https://www.emjreviews.com/oncology/article/parp-inhibitors-as-a-novel-treatment-strategy-for-patients-with-brca-mutated-metastatic-breast-cancer/