Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity

Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity

A long-standing problem is how cells that lack one of the highly similar ribosomal proteins (RPs) often display distinct phenotypes. Yeast and other organisms live longer when they lack specific ribosomal proteins, especially of the large 60S subunit of the ribosome. However, longevity is neither as...

Full description

Bibliographic Details
Main Authors: Nairita Maitra, Chong He, Heidi M Blank, Mitsuhiro Tsuchiya, Birgit Schilling, Matt Kaeberlein, Rodolfo Aramayo, Brian K Kennedy, Michael Polymenis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
ribosomal
translation
one-carbon
cell cycle
longevity
Rpl22
Online Access:https://elifesciences.org/articles/53127

Internet

https://elifesciences.org/articles/53127

Similar Items