Nuclei determine the spatial origin of mitotic waves

Nuclei determine the spatial origin of mitotic waves

Traveling waves play an essential role in coordinating mitosis over large distances, but what determines the spatial origin of mitotic waves remains unclear. Here, we show that such waves initiate at pacemakers, regions that oscillate faster than their surroundings. In cell-free extracts of Xenopus...

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Bibliographic Details
Main Authors: Felix E Nolet, Alexandra Vandervelde, Arno Vanderbeke, Liliana Piñeros, Jeremy B Chang, Lendert Gelens
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
biological waves
pacemakers
cell cycle
mitosis
biological oscillations
spatial coordination
Online Access:https://elifesciences.org/articles/52868

Internet

https://elifesciences.org/articles/52868

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