Discovery of functional non-coding conserved regions in the α-synuclein gene locus [v2; ref status: indexed, http://f1000r.es/4v9]

Several single nucleotide polymorphisms (SNPs) and the Rep-1 microsatellite marker of the α-synuclein ( SNCA) gene have consistently been shown to be associated with Parkinson’s disease, but the functional relevance is unclear. Based on these findings we hypothesized that conserved cis-regulatory el...

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Bibliographic Details
Main Authors: Lori Sterling, Michael Walter, Dennis Ting, Birgitt Schüle
Format: Article
Language:English
Published: F1000 Research Ltd 2014-12-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/3-259/v2